>> Phyllanthus Emblica
1. Merck launches new skin lightening trio.
Michelle Yeomans, 3 may 2012.
"According to Merck experts, if you want to lighten skin, you must interrupt the pigmentation formation process, therefore these three substances have been designed to influence the pigmentation process. " Each one has various PH levels, blocking the production of melanin at different sites, and can be combined with each other or other active ingredients, " says a company spokesperson. Emblica is extracted from the Phyllanthus Emblica fruit using a water based process and is suitable for skin lightening, skin care and anti-spots products."
2. Cosmeceutical Critique.
Dr.Leslie S.Baumann, march 14, 2012.
"Emblica officinalis (also known as Phyllanthus emblica, Indian gooseberry, or by its Hindi name amla)...In 2002, a standardized extract of E. officinalis (trade name, Emblica) was found to exert a long-lasting and broad-spectrum antioxidant activity, appropriate for use in antiaging, sunscreen, and general purpose skin formulations given its demonstrated capacity to protect the skin from damage engendered by free radicals, nonradicals, and transition metal-induced oxidative stress (Skin Pharmacol. Appl. Skin Physiol. 2002;15:374-80). In addition, Emblica appears to be an ideal combination of the characteristics necessary for an effective skin-lightening ingredient. Specifically, it inhibits tyrosinase and/or tyrosinase-related proteins (TRP-1 and 2) and peroxidase/H2O2 at various points in the melanogenesis pathway (Skin Pharmacol. Appl. Skin Physiol. 2002;15:374-80), and acts as a broad-spectrum cascading antioxidant. (Antioxidants comprise one group of suitable hypopigmenting agents.) Emblica, which is photochemically and hydrolytically stable, therefore suitable for inclusion in skin care formulations, is thought to be comparably efficacious to hydroquinone and kojic acid as a skin-lightening compound, but without posing the same risks or likelihood of eliciting adverse effects."
3. Inhibition of UV-induced ROS and collagen damage by Phyllanthus emblica extract in normal human dermal fibroblasts.
Muhammed Majeed, Beena Bhat, Susmitha Anand, A Sivakumar, Pritee Paliwal and K G Geetha J Cosmet Sci 62(1):49-56 (2011).
"As a part of ongoing research for novel natural cosmeceutical actives from plant extracts, this study demonstrates that Phyllanthus emblica fruit extract has shown its efficacy in protection against ultraviolet-B (UVB) irradiation-induced reactive oxygen species (ROS) and collagen damage in normal human dermal fibroblasts. At a concentration of 0.5 mg/ml, emblica extract showed a significant response of 9.5 ± 0.28-fold protection from UVB induced-collagen damage as compared to untreated cells. A known active, ascorbic acid, at a concentration of 0.5 mg/ml, showed 3.7 ± 0.07-fold protection from UVB-induced collagen damage. While the untreated cells showed 84 ± 1.4% induction in ROS on UVB irradiation as compared to the non-irradiated cells, emblica extract treatment inhibited the induction of ROS to 15 ± 4% at a concentration of 0.5 mg/ml. Ascorbic acid inhibited the induction in ROS to 64 ± 2% at a concentration of 0.5 mg/ml. Emblica extract is a significantly better natural active, with promising cosmeceutical benefits against photoaging."