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    1. Methods and Compositions for Reducing the Apperance of Dynamic Facial Wrinkles.
    Walter P.Smith, New Cannan, CT (US). Louis C.Paul 420 East 61st Street, 8E New York, NY 10021 (US). Pub.Date:Apr.23,2009.

    "Argireline (INCI Name: acetyl hexapeptide-3) is marketed by Lipotec, SA and distributed in North America by Centerchem. A Jun.18,2004 article in the New York Times entitled "New Creams Smooth Wrinkles, But They're Not Botox" quoted the CEO of Centerchem who described Argireline as having a "de-stressing effect on the skin". Among the many cosmetic products that contain Argireline are Revion's Age Defying Makeups with Botafirm (a complex comprising the acetyl hexapeptide and botanical extracts)."

    2. Topical Oligopeptide Delivery System.
    Fatemeh Mohammadi, Hauppauge, NY (US); Vasile lonita-Manzatu, Old Bethpage, NY (US); Andrew J, Bevacqua, East Setauket, NY (US); Julius R.Zecchino, Closter, NJ (US); Anna Czarnota, Huntington, NY )US); Mirela lonita-Manzatu, Old Bethpage, NY (US). The Estee Lauder Cos, INC 125 Pinelawn Road Melville, NY 11747 (US). Pub.Date:Dec.7,2006.

    "EP 1180524 discloses a group of catecholamine inhibiting oligopeptides that have the effect of reducing the appearance of lines and wrinkles on the skin. The contents of this document are incorporated by reference. These peptides are derived from the carboxy end of protein SNAP-25. Any of these peptides may be useful in connection with the patch of the invention; however, one particularly useful peptide has the formula Glu-Glu-Met-Gln-Arg-Arg. More specifically, apeptide of this type is acetyl hexapeptide3, also know commercially as Argireline, manufactured by Lipotec, and available from Centerchem(Norwalk, Conn)."

    3. Cosmeceutical value of herbal extracts as natural ingredients and novel technologies in anti-aging.
    Siavash Hosseinpour Chermahini, Fadzilah Adibah Abdul Majid and Mohamad Roji Sarmidi. Journal of Medicinal Plants Research Vol.5(14), pp.3074-3077, 18 July,2011.

    "Most innovations in anti-aging skin care are new ingredients, often totted as the next "fountain of youth". While no one has discovered how to stop or reverse aging yet, there are some ingredients that have truly transformed what is possible in anti-aging skin care. Some of the most effective ingredients (like retinoids, peptides, and antioxidants) have become leading skin aging fighters in the industry. Hydroxy acids, vitamins (like B,C, and E), hyalurinic acids, coenzyme Q10, alpha-lipoic acid, and green tea are also among the industry's staples. However, in this ever- changing landscape, there are always new additions. Some recent ones include growth factors, sirtuins, resveratrol, hydroquinone, argireline, and dimethylaminoethanol (DMAE)."